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COMPLETE: Locomotor Function Following Acute Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation in Individuals with Spinal Cord Injury

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This study is complete and is no longer recruiting subjects.

Overview

The purpose of this study is to determine if acute intermittent hypoxia therapy (AIH) combined with transcutaneous spinal cord stimulation (tSCS) during ambulation training improves locomotor function in individuals with spinal cord injury. This is a randomized, single blind, crossover trial with 3 arms:

  1. AIH + tSCS + gait training
  2. Sham AIH + tSCS + gait training
  3. Sham AIH + Sham tSCS + gait training

Subject Population

  • Diagnosed with a spinal cord injury below level C2 - ASIA Impairment Scale Grade A-D
  • 18 years of age or older
  • At least 6 months post spinal cord injury
  • Paraplegia or tetraplegia secondary to a single spinal cord injury
  • Able to provide informed consent
  • Not currently receiving regular physical therapy services

Study Personnel

Arun Jayaraman, PT, PhD

Arun Jayaraman, PT, PhD

Executive Director, Technology & Innovation Hub (tiHUB); Director, Max N?der Center for Rehabilitation Technologies & Outcomes Research

mentioned in this article

Study Partners

Milap Sandhu, PT, PhD

Milap Sandhu, PT, PhD

Research Scientist II, Shirley Ryan 小恩雅 Assistant Professor of Physical Medicine and Rehabilitation, Northwestern University

mentioned in this article

Funding Source

Shirley Ryan 小恩雅-Craig H. Nielsen Foundation Infrastructure Grant

Shirley Ryan 小恩雅 Catalyst Grant Program

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