Translational Cell Therapy Lab
Meet Mitra Lavasani, PhD
Video: The Future of Osteoarthritis
Selected Publications
Systemic Transplantation of Adult Multipotent Stem Cells Functionally Rejuvenates Aged Articular Cartilage.
Osteoarthritis (OA) is the most common and debilitating joint disease of advanced age and has no universally effective therapy. Here, we demonstrate that systemic transplantation of adult multipotent muscle-derived stem/progenitor cells (MDSPCs)-isolated from young mice-rejuvenates the knee articular cartilage (AC) of naturally aged mice. This intervention reduced expression of pro-inflammatory cytokines (Tnf and Il1a) and catabolic matrix-degrading proteinases (Mmp3 and Mmp13) in aged…
mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.
Biologic strategies to improve nerve regeneration after peripheral nerve repair.
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Latest Updates
Neural Prosthesis Seminar Series with Guest Speaker Dr. Arun Jayaraman
The Cleveland FES Center’s Neural Prosthesis Seminar Series welcomes Dr. Arun Jayaraman to discuss Innovations in Wearables, Machine Learning, and Automation.
view all newsImpact Series Spotlight: Aphasia Community Groups
The Center for Aphasia Research and Treatment offers programs that give participants the opportunity to practice communication, meet others living with aphasia, learn and have fun in a supportive environment.
IEEE Spectrum Feature on Self-Balancing Exoskeleton
In a recent article in IEEE Spectrum on a self-balancing exoskeleton by Human in Motion Robotics, Arun Jayaraman, PT, PhD, Director of the Max N?der Center for Rehabilitation Technologies and Outcomes Research, provided insights on at-home use of self-balancing exoskeletons.